Jervine

Size

£182.00

SKU:: 10-2388
Additional Names:: 11-Ketocyclopamine
Physical State:: Solid
Molecular Weight:: 425.62
Purity:: 98%
Storage Conditions:: -20[o]C
Supplier:: Focus Biomolecules
CAS Number:: 469-59-0
Immunogen:: GPCR
Extra Details:: Inhibitor of Hedgehog signaling (IC50 = 0.5-0.7 uM). Binds directly to Smoothened (Smo)1. Inhibits the response of target tissues to Sonic hedgehog signaling2. Induces COX-2 overexpression in human erythroleukemia cells3.