10-2387
Nocodazole
Size
£149.00
- SKU:
- 10-2387
- Additional Names:
- R-17934
- Physical State:
- Solid
- Molecular Weight:
- 301.32
- Purity:
- 98%
- Storage Conditions:
- RT
- Supplier:
- Focus Biomolecules
- CAS Number:
- 31430-18-9
- Immunogen:
- Cytoskeleton|Lysosome
- Extra Details:
- Nocodazole is an antimitotic agent that disrupts microtubules by binding to B Beta tubulin and thereby inhibiting microtubule dynamics, disruption of mitotic spindle function, and fragmentation of the Golgi complex.1,2 Arrests cell cycle at G2/M phase. Stimulates the intrinsic GTPase activity of tubulin.3 Nocodazole activates the JNK/SAPK signaling pathway and induces apoptosis in a variety of cell lines.4 Increases Cas9-mediated editing frequencies5 and increased CRISPR-mediated HDR DNA repair6. Cell permeable.
- Shipping Conditions:
- Ambient