10-2311
Honokiol
Size
£153.00
- SKU:
- 10-2311
- Additional Names:
- NSC-293100
- Physical State:
- Solid
- Molecular Weight:
- 266.34
- Purity:
- >98%
- Storage Conditions:
- -20[o]C
- Supplier:
- Focus Biomolecules
- CAS Number:
- 35354-74-6
- Immunogen:
- Protein deacetylase|Transcription factor
- Extra Details:
- Honokiol is a natural product that acts as a SIRT3 activator. It increases mitochondrial oxygen consumption and reduces ROS production in wild type but not SIRT3-KO cells.1 It reversed cardiac hypertrophy in mice1 and rescued myocardial and mitochondrial energetics in type 2 diabetic rats2. It was shown to increase SIRT3 expression in the hippocampus and attenuated surgery-induced memory loss, neuronal apoptosis, neuroinflammation and oxidative damage.3 It increases expression of adipocyte gene markers, gene-involved lipolysis and glucose transport and in general, promotes insulin sensitivity.4
- Shipping Conditions:
- Ambient