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10-2277

Rotenone

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£147.00

SKU:
10-2277
Additional Names:
Nicouline|NSC-26285
Physical State:
Solid
Molecular Weight:
394.42
Purity:
>98%
Purification:
HPLC Purified
Storage Conditions:
RT
Supplier:
Focus Biomolecules
CAS Number:
83-79-4
Immunogen:
Energy production
Extra Details:
Rotenone (83-79-4), the most common member of the rotenoid natural product family, inhibits complex I of the mitochondrial electron transport chain (IC50 = 1.7 - 2.2 uM).1 Also inhibits NADH oxidation by cardiac sarcoplasmic reticulum (IC50 = 3.4 nM).2 May be used to induce Parkinsonism in animal models.3,4 Inhibits autophagy by blocking lysosomal degradation of autophagic vacuoles.5
Shipping Conditions:
Ambient