10-2277
Rotenone

Size
£147.00
- SKU:
- 10-2277
- Additional Names:
- Nicouline|NSC-26285
- Physical State:
- Solid
- Molecular Weight:
- 394.42
- Purity:
- >98%
- Purification:
- HPLC Purified
- Storage Conditions:
- RT
- Supplier:
- Focus Biomolecules
- CAS Number:
- 83-79-4
- Immunogen:
- Energy production
- Extra Details:
- Rotenone (83-79-4), the most common member of the rotenoid natural product family, inhibits complex I of the mitochondrial electron transport chain (IC50 = 1.7 - 2.2 uM).1 Also inhibits NADH oxidation by cardiac sarcoplasmic reticulum (IC50 = 3.4 nM).2 May be used to induce Parkinsonism in animal models.3,4 Inhibits autophagy by blocking lysosomal degradation of autophagic vacuoles.5
- Shipping Conditions:
- Ambient
