10-2236
Ibudilast
Size
£139.00
- SKU:
- 10-2236
- Additional Names:
- 2-Methyl-1-[2-(1-methylethyl)pyrazolo[1,5-a]pyridine-3-yl 1-propanone|AV411|KC-404
- Physical State:
- Solid
- Molecular Weight:
- 230.31
- Purity:
- 98%
- Purification:
- HPLC Purified
- Storage Conditions:
- RT
- Supplier:
- Focus Biomolecules
- CAS Number:
- 50847-11-5
- Immunogen:
- PDE (Phosphodiesterase)
- Extra Details:
- Phosphodiesterase inhibitor with some selectivity for PDE4 and 5. (IC50s= 53, 35, 48,12 and10 uM for PDE 1a, 2, 3, 4 and 5 respectively1). Acts as a cerebral vasodilator by selectively inducing a cGMP-independent relaxation of the intracranial vertebrobasilar artery.2 Attenuates neuroinflammation and enhances retinal ganglion cell viability in glaucoma via PKA signaling.3 A glial cell activation inhibitor.4 Enhances morphine analgesia and attenuates tolerance and withdrawaI.5 Orally active and crosses the blood-brain barrier.5
- Shipping Conditions:
- Ambient