Tryptanthrin

Size

£153.00

SKU:: 10-2228
Additional Names:: Couroupitine A|NSC 349447
Physical State:: Solid
Molecular Weight:: 248.24
Purity:: 98%
Purification:: HPLC Purified
Storage Conditions:: -20[o]C
Supplier:: Focus Biomolecules
CAS Number:: 13220-57-0
Immunogen:: Tryptophan
Extra Details:: A indoloquinazoline alkaloid found in various plant species and possessing intriguing pharmacological activities.1 Suppresses activation of BV2 microglia cells following LPS treatment and reduces production of proinflammatory cytokines via Nrf2, HO-1 and NFK KappaB signaling.2 Displays antiinflammatory activity targeting IL-17.3 Inhibits indoleamine 2,3-dioxygenase 2 (IDO2) with an IC50 of 5-17 uM.4 Induces growth inhibition and neuronal differentiation in human neuroblastoma LA-N-1 cells.5