10-2204
Cisplatin
Size
£149.00
- SKU:
- 10-2204
- Additional Names:
- CDDP|cis-Diamineplatinum(II) dichloride
- Physical State:
- Solid
- Molecular Weight:
- 300.05
- Purity:
- 98%
- Purification:
- HPLC Purified
- Storage Conditions:
- RT
- Supplier:
- Focus Biomolecules
- CAS Number:
- 15663-27-1
- Immunogen:
- DNA
- Extra Details:
- Induces intra- and interstrand DNA adducts which poison topoisomerase I.1 Synergizes with topoisomerase I inhibitors such as topotecan.1 Induces apoptosis by sequential activation of caspase-8, -3 and -6 in osteosarcoma cells.2 Inhibits expression of X-linked inhibitor of apoptosis protein (XIAP) in human LNCaP cells.3 Numerous mechanisms inhibit propagation of cisplatin-induced DNA damage to signal apoptosis resulting in resistance.4 Clinically useful anticancer agent.
- Shipping Conditions:
- Ambient