10-2199
Ansamitocin P3
Size
£149.00
- SKU:
- 10-2199
- Physical State:
- Solid
- Molecular Weight:
- 635.16
- Purity:
- >90%
- Storage Conditions:
- -20[o]C
- Supplier:
- Focus Biomolecules
- CAS Number:
- 66584-72-3
- Immunogen:
- Antibiotic|Cytoskeleton
- Extra Details:
- Ansamitocin P3 (66547-09-9) is a fungal metabolite from Actinosynnema pretiosum which binds to the phomopsin A/rhizoxin site on tubulin1,2. Ansamitocin P3 is a maytansine analog which displays potent cytotoxicity against various human tumor cell lines2,3. Maytansine and its analogs cause extensive disassembly of microtubules and totally prevent tubulin spiralization4.
- Shipping Conditions:
- Ambient