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10-2185

Vandetanib

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£149.00

SKU:
10-2185
Additional Names:
ZD6474
Physical State:
Solid
Molecular Weight:
475.35
Purity:
98%
Storage Conditions:
-20[o]C
Supplier:
Focus Biomolecules
CAS Number:
443913-73-3
Immunogen:
Kinase
Extra Details:
A potent and selective inhibitor of VEGFR2, (KDR IC50 = 40 nM). Also inhibits fms-like tyrosine kinase 4 (VEGFR3, IC50 = 110 nM) and epidermal growth factor receptor (EGFR/HER1, IC50 = 500 nM) but shows selectivity against a panel of other tyrosine and serine-threonine kinases. Inhibits colony formation in seven cancer cell lines2. Displays anti-angiogenesis activity3.
Shipping Conditions:
Ambient