10-2173
SB 203580
Size
£158.00
- SKU:
- 10-2173
- Physical State:
- Solid
- Molecular Weight:
- 377.44
- Purity:
- 98%
- Storage Conditions:
- -20[o]C
- Supplier:
- Focus Biomolecules
- CAS Number:
- 152121-47-6
- Immunogen:
- Kinase
- Extra Details:
- A potent and selective inhibitor of p38 MAP kinase, IC50=50 and 500 nM for p38 and p38B Beta2 respectively. No other kinases (in a panel of 30) were significantly inhibited including p38G Gamma and D Delta at 10 uM2. A potent inhibitor of inflammatory cytokine production (IC50=15-25 mg/kg in mice and rats) in animal models of arthritis, bone resorption, endotoxin shock and immune function3.
- Shipping Conditions:
- Ambient