PD-98059

Size

£144.00

SKU:: 10-2159
Additional Names:: 2'-Amino-3'-methoxyflavone
Physical State:: Solid
Molecular Weight:: 267.29
Purity:: 98%
Storage Conditions:: RT
Supplier:: Focus Biomolecules
CAS Number:: 167869-21-8
Immunogen:: Kinase
Extra Details:: Inhibitor of mitogen-activated protein kinase kinase (MKK / MEK). Acts via binding to the inactivated form of MEK, preventing its phosphorylation by cRAF or MEK kinase (IC50=2-7M).1,2 Accelerates differentiation of RAW264.7 cells into osteoclast-like cells.3 Mimics BMP4 in supporting self renewal of embryonic stem cells4.