10-2154
Olaparib
Size
£144.00
- SKU:
- 10-2154
- Additional Names:
- AZD-2281|KU-59436
- Physical State:
- Solid
- Molecular Weight:
- 434.47
- Purity:
- 98%
- Storage Conditions:
- -20[o]C
- Supplier:
- Focus Biomolecules
- CAS Number:
- 763113-22-0
- ABP:
- No Import Docs
- Immunogen:
- PARP
- Extra Details:
- A highly potent and selective PARP-inhibitor with IC₅₀ values of 5 nM and 1 nM for PARP-1 and PARP-2, respectively.1 In a genetically engineered mouse model for BRCA1-associated breast cancer olaparib inhibited tumor growth and improved survival with no signs of toxicity.2 Synergizes with many other anticancer agents.3 Shows efficacy in colorectal cancers.4 Prevents house dust mite allergen-induced asthma in a mouse model.5
- Shipping Conditions:
- Ambient