10-2135
Erlotinib HCl
Size
£134.00
- SKU:
- 10-2135
- Physical State:
- Solid
- Molecular Weight:
- 429.91
- Purity:
- 98%
- Storage Conditions:
- -20[o]C
- Supplier:
- Focus Biomolecules
- CAS Number:
- 183319-69-9
- Immunogen:
- Kinase
- Extra Details:
- Potent inhibitor of EGFR tyrosine kinase (IC50 = 2 nM)1. Potent inhibitor of mutant JAK2-V617F2. Weaker inhibitor of ErbB-2 kinase (Ki = 1 uM) ErbB-4 kinase (Ki = 1.5 uM)3. HDAC inhibitors sensitize for erlotinib activity in EGFR-mutated and wildtype non-small cell lung cancer (NSCLC) cells4. A clinically effective agent for NSCLC5.
- Shipping Conditions:
- Ambient