10-2132
Enzastaurin
Size
£158.00
- SKU:
- 10-2132
- Additional Names:
- LY-317615
- Physical State:
- Solid
- Molecular Weight:
- 515.61
- Purity:
- 99%
- Purification:
- HPLC Purified
- Storage Conditions:
- -20[o]C
- Supplier:
- Focus Biomolecules
- CAS Number:
- 170364-57-5
- Immunogen:
- Kinase
- Extra Details:
- Potent and selective PKCB Beta inhibitor. IC50 = 6, 39, 83 and 110 nM, for PKCB Beta, PKCA Alpha, PKCG Gamma and PKCE Epsilon respectively.1 Induces apoptosis in multiple myeloma cell lines via inhibition of the AKT signaling pathway.2 Induces mitotic missegregation and preferential cytotoxicity in colorectal cancer cells with chromosomal instability.3 Attenuates ampheta-mine-stimulated dopamine efflux.4 Inhibits blood-brain barrier leakiness in a mouse model.5
- Shipping Conditions:
- Ambient