Streptozotocin

Size

£197.00

SKU:: 10-2127
Additional Names:: Streptozocin|U-9889
Physical State:: Solid
Molecular Weight:: 265.22
Purity:: 97%
Storage Conditions:: -20[o]C
Supplier:: Focus Biomolecules
CAS Number:: 18883-66-4
Immunogen:: Antibiotic|DNA|Glycosylation
Extra Details:: An N-nitroso-aminoglucose derivative which is used to produce animal models of diabetes.1 Alkylates DNA.2 Inhibits pancreatic B Beta-cell O-Glc-NAc selective N-acetyl-B Beta-D-glucosaminidase.3 Selectively induces death of B Beta-cells which mechanistically is independent of N-acetyl-B Beta-D-glucosaminidase inhibition.4 Is not a spontaneous NO donor.5