10-2114
Withaferin A
Size
£163.00
- SKU:
- 10-2114
- Additional Names:
- NSC-101088
- Physical State:
- Solid
- Molecular Weight:
- 470.60
- Purity:
- 99%
- Purification:
- HPLC Purified
- Storage Conditions:
- -20[o]C
- Supplier:
- Focus Biomolecules
- CAS Number:
- 5119-48-2
- Immunogen:
- Cytoskeleton
- Extra Details:
- Displays potent antiangiogenesis activity inhibiting endothelial cell sprouting in vitro (IC50 = 12 nM) and in vivo.1 Potently inhibits NF-K KappaB activation by preventing TNFA Alpha-induced activation of IKKB Beta.2 Covalently binds to the intermediate filament protein, vimentin3 inducing its disassembly and serine 56 phosphorylation4. Inhibits reactive gliosis and blocks TNFA Alpha-mediated neuronal apoptosis in in vivo models.5
- Shipping Conditions:
- Ambient