10-2111
Tunicamycin
Size
£182.00
- SKU:
- 10-2111
- Physical State:
- Solid
- Molecular Weight:
- Avg 840.0
- Purity:
- 99%
- Storage Conditions:
- -20[o]C
- Supplier:
- Focus Biomolecules
- CAS Number:
- 11089-65-9
- Immunogen:
- Antibiotic|ER/Golgi|UPR (Unfolded Protein Response)
- Extra Details:
- Fermentation product from Streptomyces lysosuperificus. Provided as a mixture of tunicamycin A (C14), B (C15), C (C16) and D (C17) homologs varying in the number of carbon atoms in the fatty acid chain. The structure shown above is for tunicamycin B (the C15 homolog) Potent inhibitor of GlcNAc phosphotransferase which thereby inhibits glycoprotein biosynthesis1. Causes endoplasmic reticulum stress-induced autophagy2 and unfolded protein response3. Arrests cell cycle in late G14.
- Shipping Conditions:
- Ambient