10-2102
Radicicol
Size
£149.00
- SKU:
- 10-2102
- Additional Names:
- Monorden
- Physical State:
- Solid
- Molecular Weight:
- 364.78
- Purity:
- 99%
- Purification:
- HPLC Purified
- Storage Conditions:
- -20[o]C
- Supplier:
- Focus Biomolecules
- CAS Number:
- 12772-57-5
- Immunogen:
- HSP (Heat shock protein)|Kinase
- Extra Details:
- Radicicol inhibits heat shock protein 90 (Hsp90) activity by binding to the ATP-binding pocket.1 In cells Hsp90 client proteins such as Raf kinase2, HIF-1A Alpha3 and estrogen receptor4 are destabilized and proteolytically degraded. Inhibits expression of COX-2 without affecting COX-1 expression in LPS-stimulated macrophages (IC50=27 nM).5 Inhibits angiogenesis.6
- Shipping Conditions:
- Ambient