10-2085
Mithramycin A
Size
£141.00
- SKU:
- 10-2085
- Additional Names:
- A2371|Antibiotic LA 7017|Aureolic Acid|NSC 24559|PA 144|Plicamycin
- Physical State:
- Solid
- Molecular Weight:
- 1085.15
- Purity:
- 98%
- Purification:
- HPLC Purified
- Storage Conditions:
- -20[o]C
- Supplier:
- Focus Biomolecules
- CAS Number:
- 18378-89-7
- Immunogen:
- DNA|Methyltransferase|Nucleic acid methylation
- Extra Details:
- Inhibits DNA methyl transferase1. A selective Sp1 inhibitor, it binds to GC rich DNA sequences, displacing Sp1 transcription factor binding to oncogene promoters, inhibitings their expression2. Mithramycin A (at 10-200 nM) sensitizes tumor cells to TRAIL-induced apoptosis3.
- Shipping Conditions:
- Ambient