10-2076
Gliotoxin
Size
£182.00
- SKU:
- 10-2076
- Additional Names:
- Aspergillin
- Physical State:
- Lyophilized
- Molecular Weight:
- 326.39
- Purity:
- 98%
- Purification:
- HPLC Purified
- Storage Conditions:
- -20[o]C
- Supplier:
- Focus Biomolecules
- CAS Number:
- 67-99-2
- Immunogen:
- Antibiotic|Nox (NADH/NADPH oxidase)|Protease
- Extra Details:
- A fungal metabolite with immunosuppressive properties; blocks phagocytosis, cytokine production and proliferation of T and B cells.1 Inhibits chymotrypsin-like activity of 20S proteasome preventing IK KappaBA Alpha degradation and preventing NF-K KappaB degradation2. Displays antiinflammatory activity3 and blocks leukotriene B4 production via inhibition of LTA4 hydrolase4. It inhibits nuclear NOTCH2 and recovers a tumor-suppressor NOTCH3 activity in chronic lymphocytic leukemia cells.5
- Shipping Conditions:
- Ambient