10-2058
Aphidicolin
Size
£190.00
- SKU:
- 10-2058
- Physical State:
- Solid
- Molecular Weight:
- 338.48
- Purity:
- 98%
- Storage Conditions:
- -20[o]C
- Supplier:
- Focus Biomolecules
- CAS Number:
- 38966-21-1
- Immunogen:
- Antibiotic|DNA
- Extra Details:
- Aphidicolin specifically inhibits DNA polymerase A Alpha and D Delta via binding to the enzyme, in eukaryotic cells such as the HeLa cell line, without affecting other DNA polymerases1. Arrests cell cycle at early S phase while allowing continued cell growth2. Potentiates apoptosis induction induced by other agents3. Increases gene amplification frequency in HeLa S3 cells overexpressing Bcl-24.
- Shipping Conditions:
- Ambient