10-2057
Apicidin
Size
£153.00
- SKU:
- 10-2057
- Physical State:
- Solid
- Molecular Weight:
- 623.78
- Purity:
- >98%
- Storage Conditions:
- -20[o]C
- Supplier:
- Focus Biomolecules
- CAS Number:
- 183506-66-3
- Immunogen:
- Protein deacetylase
- Extra Details:
- Apicidin is a fungal toxin that is a potent, cell permeable inhibitor of histone deacetylases (HDAC's).1 It also displays antitumor properties by inducing changes in p21WAF1/Cip1 and gelsolin gene expression causing cell cycle arrest in the G1 phase.2 Apicidin dramatically decreases HIF-1A Alpha protein levels and transcriptional activity in human and mouse tumor cell lines.3
- Shipping Conditions:
- Ambient