10-2049
Candesartan
Size
£139.00
- SKU:
- 10-2049
- Additional Names:
- CV-11974
- Physical State:
- Solid
- Molecular Weight:
- 400.45
- Purity:
- 98%
- Storage Conditions:
- -20[o]C
- Supplier:
- Focus Biomolecules
- CAS Number:
- 139481-59-7
- Immunogen:
- GPCR
- Extra Details:
- Angiotensin II receptor I (AT1) antagonist, IC50s=1.12 and 2.86 nM for bovine adrenal cortex and rabbit aorta respectively.1 Selectively inhibits angiotensin II-induced contraction of rabbit aortic strips with no effect on contraction induced by other agents such as norepinephrine, KCl, serotonin, PGF2A Alpha or endothelin. Prevents astrocyte and microglial activation and neuroinflammation and improves hippocampal neurogenesis.2 Attenuates angiogenesis in hepatocellular carcinoma.3 Clinically useful antihypertensive agent. Ameliorates brain inflammation associated with Alzheimer's disease.4 Active in vivo and orally active.
- Shipping Conditions:
- Ambient