Ezetimibe

Size

£153.00

SKU:: 10-2027
Additional Names:: Ezetrol|SCH 58235
Physical State:: Solid
Molecular Weight:: 409.43
Purity:: 98%
Storage Conditions:: RT
Supplier:: Focus Biomolecules
CAS Number:: 163222-33-1
Immunogen:: Inflammasome
Extra Details:: Inhibits cholesterol absorption in the intestine by preventing cholesterol uptake by the Niemann-Pick C1-like 1 (NPC1L1) protein, a cholesterol transporter.1 Undergoes rapid glucuronidation in the intestine where its glucuronide binds NPC1L1.2 Inhibits dengue virus infection in Huh-7 cells by blocking cholesterol transport.3 Ameliorates steatohepatitis by activation of autophagy and inhibition of NLRP3 inflammasome.4