2',3'-cGAMP

Size

£158.00

SKU:: 10-1639
Additional Names:: 2',3'cyclic GMP-AMP
Physical State:: Solid
Molecular Weight:: 718.38
Purity:: 98%
Purification:: HPLC Purified
Storage Conditions:: -20[o]C
Supplier:: Focus Biomolecules
CAS Number:: 1441190-66-4
Immunogen:: STING
Extra Details:: 2',3'-cGAMP (CAS 1441190-66-4) is an endogenous STING (stimulator of interferon genes) agonist.1 Produced from ATP and GTP via the action of cGMP-AMP synthase (cGAS) which acts as a cytosolic DNA sensor.2,3 Induces autophagy which is a mechanism for clearance of DNA and viruses in the cytosol.4 DNA damage stimulates 2',3'-cGAMP which stimulates an inflammatory response.5