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10-1613

Fasnall HCl

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£164.00

SKU:
10-1613
Physical State:
Solid
Molecular Weight:
374.93
Purity:
98%
Storage Conditions:
-20[o]C
Supplier:
Focus Biomolecules
CAS Number:
929978-58-5
Extra Details:
Potent and selective fatty acid synthase (FASN) inhibitor acting via interfering with cofactor binding.1 IC50s = 147 and 213 nM respectively for inhibition of acetate and glucose incorporation into total lipids in HepG2 cells. IC50=5.84 uM in an isolated enzyme assay. Displays potent antitumor activity in the MMTV-Neu HER2+ breast cancer model.1 Reduces HIV-1 virion production by 90% (EC50=213 nM).2
Shipping Conditions:
Ambient