10-1600
CaCCinh-A01
Size
£149.00
- SKU:
- 10-1600
- Physical State:
- Solid
- Molecular Weight:
- 347.43
- Purity:
- >98%
- Storage Conditions:
- -20[o]C
- Supplier:
- Focus Biomolecules
- CAS Number:
- 407587-33-1
- Immunogen:
- Ion channel
- Extra Details:
- CaCCInh-A01 is a potent inhibitor of TMEM16A (IC50 = 2.1 mM), a calcium-activated chloride channel1. Blockade of TMEM16A with CaCCInh-A01 protects against renal fibrosis2, reduces blood brain barrier permeability, attenuates brain infarct size and neurological deficits after ischemic stroke3, and induces apoptosis and cell cycle arrest in various epithelium-originated cancer cells4.
- Shipping Conditions:
- Ambient