TG 4-155

Size

£149.00

SKU:: 10-1574
Physical State:: Solid
Molecular Weight:: 394.47
Purity:: 98%
Storage Conditions:: -20[o]C
Supplier:: Focus Biomolecules
CAS Number:: 1164462-05-8
Immunogen:: GPCR
Extra Details:: Potent and selective prostaglandin EP2 receptor antagonist, KB = 2.4 and 34.5 nM for EP2 and DP1 receptors respectively. Displays >500-fold selectivity for EP2 over other prostanoid receptors.1 Inhibits butaprost-induced proinflammatory cytokine production, cell proliferation and invasion of PC-3 cells in vitro.2 Inhibits PGE2-induced inflammatory response and may represent a novel pharmacologic intervention for tumorigenesis resulting from inflammation.1