10-1567
Compound 115-7c
Size
£187.00
- SKU:
- 10-1567
- Additional Names:
- SW02
- Physical State:
- Solid
- Molecular Weight:
- 477.34
- Purity:
- 98%
- Storage Conditions:
- -20[o]C
- Supplier:
- Focus Biomolecules
- CAS Number:
- 908074-72-6
- Immunogen:
- Chaperone|HSP (Heat shock protein)
- Extra Details:
- Acts as an artificial co-chaperone for HSP701. The activity of compound 115-7c mirrors those of HSP40 stimulating the ATPase and protein-folding activities of prokaryotic HSP70. Increases tau levels in cell lines overexpressing tau2. Induces solubilization of polyglutamine and exacerbates polyQ-mediated toxicity3,4. An important probe for understanding HSP70 functions4
- Shipping Conditions:
- Ambient