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10-1563

Ro 31-8425 HCl

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£149.00

SKU:
10-1563
Additional Names:
BIM X|Bisindolylmaleimide X
Physical State:
Solid
Molecular Weight:
460.96
Purity:
98%
Storage Conditions:
-20[o]C
Supplier:
Focus Biomolecules
CAS Number:
145317-11-9
Immunogen:
Kinase
Extra Details:
Selective, reversible, ATP-competitive inhibitor of protein kinase C. Inhibits PKCA Alpha, B Beta1, B Beta2, G Gamma and E Epsilon, IC50= 8, 8, 14,13 and 39 nM respectively.1 Extremely useful tool for probing PKC-dependent physiology2 or signaling pathways3. Increases MSC adhesion to an ICAM-1 coated substrate in vitro and enables targeted delivery of systematically administered MSCs to inflamed sites in vivo in a CD11a-dependent manner.4 Cell permeable.
Shipping Conditions:
Ambient