10-1555
ML241
Size
£187.00
- SKU:
- 10-1555
- Additional Names:
- CID49830260
- Physical State:
- Solid
- Molecular Weight:
- 372.46
- Purity:
- 98%
- Purification:
- HPLC Purified
- Storage Conditions:
- -20[o]C
- Supplier:
- Focus Biomolecules
- CAS Number:
- 1346528-06-0
- Immunogen:
- ATPase|ER/Golgi|UPR (Unfolded protein response)
- Extra Details:
- Potent and selective p97 AAA ATPase inhibitor, IC50=100 nM. Inhibits degradation of a p97-dependent but not p97-independent proteasome substrate in a dual-reporter cell line1. It impairs the endoplasmic reticulum-associated degradation (ERAD) pathway.1 ML241 and related inhibitors (DBeQ for example) have differential responses to p97 mutants as well as the presence of cofactors suggesting the possibility of context-dependent p97 inhibitors.2,3
- Shipping Conditions:
- Ambient