UCF-101

Size

£166.00

SKU:: 10-1544
Physical State:: Solid
Molecular Weight:: 495.51
Purity:: 98%
Storage Conditions:: -20[o]C
Supplier:: Focus Biomolecules
CAS Number:: 313649-08-0
Immunogen:: Protease
Extra Details:: UCF-101 is a potent, specific, competitive, and reversible inhibitor of the pro-apoptotic, mitochondrial serine protease Omi/HtrA2 (IC50 = 9.5 uM for His-Omi134-458). Shows very little activity against various other serine proteases tested (IC50 ≥ 200 uM).1 Mitigates streptozotocin-induced cardiomyocyte dysfunction.2 Protects against cerebral oxidative injury and cognitive impairment in a rat model.3 Cell permeable.