10-1543
BTB-1
Size
£139.00
- SKU:
- 10-1543
- Additional Names:
- NSC 156750
- Physical State:
- Solid
- Molecular Weight:
- 297.71
- Purity:
- 98%
- Purification:
- HPLC Purified
- Storage Conditions:
- RT
- Supplier:
- Focus Biomolecules
- CAS Number:
- 86030-08-2
- ABP:
- No Import Docs
- Immunogen:
- Cytoskeleton
- Extra Details:
- A selective, ATP-competitive and reversible inhibitor of mitotic kinesin Kif18A, IC50=1.7 M.1,2 Binds to an allosteric site near Kif18A loop 5 preventing a range of conformational changes thereby blocking motor function.3 Inhibits the differentiation of mouse bone marrow cells to dendritic cells.4 Suppresses the replication of influenza A virus, inhibiting activation of AKT, p38 MAPK, SAPK and RanBP3 leading to the prevention of nuclear export of viral ribonucleoprotein complexes. Greatly improves the viability of IAV-infected mice.5
- Shipping Conditions:
- Ambient