10-1530
NSC33994
Size
£182.00
- SKU:
- 10-1530
- Additional Names:
- G6
- Physical State:
- Solid
- Molecular Weight:
- 436.65
- Purity:
- 98%
- Storage Conditions:
- -20[o]C
- Supplier:
- Focus Biomolecules
- CAS Number:
- 82058-16-0
- Immunogen:
- Cytoskeleton|Kinase
- Extra Details:
- A remarkably potent and selective JAK2 inhibitor (IC50 = 60 nM). Displays no effect on Src and TYK2 tyrosine kinase activity at a concentration of 25 uM1. Suppresses JAK2-V617F-mediated human pathological cell growth in vitro and in vivo2 and is concomitant with the disruption of intracellular vimentin filaments3. Reduces the tumorigenic potential of T98G glioblastoma cells in vitro and in vivo4.
- Shipping Conditions:
- Ambient