DZNep

Size

£237.00

SKU:: 10-1524
Additional Names:: 3-Deazaneplanocin A, HCl|NSC 617989
Physical State:: Solid
Molecular Weight:: 298.73
Purity:: 98%
Purification:: HPLC Purified
Storage Conditions:: -20[o]C
Supplier:: Focus Biomolecules
CAS Number:: 120964-45-6
Immunogen:: Protein methyltransferase
Extra Details:: Potent histone methyltransferase inhibitor which decreases global histone methylation1. Inhibits trimethylation of H3K27 and H4K20 in vitro1. Selectively induces apoptosis in multiple cancer cell lines with no effect on normal cells2. May be used in cocktails to chemically induce pluripotent stem cells (CiPSCs) from somatic cells3. Enhances angiogenesis in a mouse model of limb ischemia4.