10-1517
Fascaplysin
Size
£139.00
- SKU:
- 10-1517
- Physical State:
- Solid
- Molecular Weight:
- 306.75
- Purity:
- 98%
- Storage Conditions:
- -20[o]C
- Supplier:
- Focus Biomolecules
- CAS Number:
- 114719-57-2
- Immunogen:
- Kinase
- Extra Details:
- A novel marine natural product isolated from Thorectandra sp1. A potent and selective inhibitor of cyclin dependent kinase 4/cyclin D1 (IC50 = 0.35 uM) and is less selective for Cdk6/D1 (IC50 = 3.4 uM). Displays antiangiogenic acitivity2. Displays high cytotoxic activity against small cell lung cancer cell lines acting via multiple mechanisms including topoisomerase I, DNA integrity and ROS3.
- Shipping Conditions:
- Ambient