10-1515
PD-150606
Size
£167.00
- SKU:
- 10-1515
- Physical State:
- Solid
- Molecular Weight:
- 306.12
- Purity:
- 98%
- Storage Conditions:
- -20[o]C
- Supplier:
- Focus Biomolecules
- CAS Number:
- 179528-45-1
- Immunogen:
- Protease
- Extra Details:
- A selective, cell-permeable non-peptide calpain inhibitor (Ki for u- and m-calpains = 0.21 and 0.37 uM respectively). Acts at the calcium binding site of calpain rather than the substrate-binding site. Inhibits calpain activity in two intact cell systems. Attenuates hypoxic/hypoglycemic injury to cerebrocortical neurons in culture and excitotoxic injury to Purkinje cells in cerebellar slices1. Displays cytoprotective effects in oxidant- and calcium ionophore-induced cell death2. Some protective effects may be due to inhibition of MMP activity3.
- Shipping Conditions:
- Ambient