10-1510
STF-083010
Size
£149.00
- SKU:
- 10-1510
- Physical State:
- Solid
- Molecular Weight:
- 317.39
- Purity:
- 98%
- Storage Conditions:
- RT
- Supplier:
- Focus Biomolecules
- CAS Number:
- 307543-71-1
- Immunogen:
- RNA|UPR (Unfolded Protein Response)
- Extra Details:
- A novel small molecule inhibitor of IRE1. It inhibits IRE1 endonuclease activity but not its kinase activity after endoplasmic reticulum stress1-3. It displays significant antimyeloma activity in model human MM xenografts1. Induces apoptosis in pancreatic cancer cells and displays growth inhibition in a clonogenic growth assay in soft agar as well as in a xenograft in vivo model of pancreatic cancer4. Active in vivo.
- Shipping Conditions:
- Ambient