10-1507
Pyocyanine
Size
£158.00
- SKU:
- 10-1507
- Additional Names:
- Pyocyanin|Sanasin|Sanazin
- Physical State:
- Solid
- Molecular Weight:
- 210.23
- Purity:
- 98%
- Purification:
- HPLC Purified
- Storage Conditions:
- -20[o]C
- Supplier:
- Focus Biomolecules
- CAS Number:
- 85-66-5
- Immunogen:
- Antibiotic
- Extra Details:
- Pyocyanine, a redox-active phenazine produced by P. aeruginosa and other pathogens, is an electron receptor, which stimulates redox cycling in bacteria as well as in a variety of human cell lines. It enhances oxidative metabolism, which increases the formation of intracellular reactive oxygen species (ROS) via reduction of NADPH. Pyocyanine accelerates neutrophil apoptosis in vitro. Pyocyanine production by P. aeruginosa suppresses the acute inflammatory response by pathogen-driven acceleration of neutrophil apoptosis and associated reduction of local inflammation.
- Shipping Conditions:
- Ambient