AI-3

Size

£173.00

SKU:: 10-1497
Physical State:: Solid
Molecular Weight:: 292.81
Purity:: 98%
Storage Conditions:: -20[o]C
Supplier:: Focus Biomolecules
CAS Number:: 882288-28-0
Immunogen:: Transcription factor
Extra Details:: Activator of antioxidant response element (ARE) which induces cytoprotective genes in human cells. It alkylates Keap1 at Cys151 and is reactive toward additional cysteines at higher concentrations. Disrupts Nrf2/Keap1 and Keap1/Cul3 interactions and stabilizes Nrf2. Activates ARE in an Nrf2 and PI 3-kinase dependent manner. Cell permeable and active in vivo.