LY364947

Size

£173.00

SKU:: 10-1492
Additional Names:: HTS-466284
Physical State:: Solid
Molecular Weight:: 272.31
Purity:: 98%
Storage Conditions:: RT
Supplier:: Focus Biomolecules
CAS Number:: 396129-53-6
Immunogen:: Kinase
Extra Details:: Selective ALK5 inhibitor, IC50 = 59, 400 and 1400 nM for TGF-B Beta RI, TGF-B Beta RII and MLK-7K, respectively1. Inhibits Smad2 phosphorylation induced by TGF-B Beta as well as fibronectin expression and MDA-MB-231 cell invasion2. Abolishes resistance of glioblastoma-initiating cells to radiation3. Cell permeable.