10-1488
Indirubin-3'-monoxime
Size
£158.00
- SKU:
- 10-1488
- Additional Names:
- Indirubin-3'oxime
- Physical State:
- Solid
- Molecular Weight:
- 277.29
- Purity:
- 98%
- Storage Conditions:
- -20[o]C
- Supplier:
- Focus Biomolecules
- CAS Number:
- 160807-49-8
- Immunogen:
- Kinase
- Extra Details:
- A potent GSK-3B Beta inhibitor (IC50=22 nM)1. Also inhibits CDK1 (IC50=180 nM) and CDK5 (IC50=100 nM)1. Displays antimitotic properties and induces endoreplication following prophase arrest in HBL-100 cells2. Possesses antiangiogenic activity3. Attenuates B Beta-amyloid-associated neuropathology in a mouse model of Alzheimer's disease4. Cell permeable.
- Shipping Conditions:
- Ambient