10-1473
YM-155
Size
£156.00
- SKU:
- 10-1473
- Additional Names:
- Sepantronium bromide
- Physical State:
- Solid
- Molecular Weight:
- 443.30
- Purity:
- >98%
- Storage Conditions:
- -20[o]C
- Supplier:
- Focus Biomolecules
- CAS Number:
- 781661-94-7
- Extra Details:
- A novel small molecule survivin suppressant. YM-155 suppresses expression of survivin (a member of the IAP family) and induced apoptosis in human tumor cell lines at 10 nmol/L with little effect on other IAP or Bcl-2 family members.1 Overcomes erlotinib resistance in EGFR mutation-positive non-small cell lung cancer.2 Induces DNA damage.3 Induces an autophagy-dependent cell death in adenoid cystic carcinoma cells.4
- Shipping Conditions:
- Ambient