Skip to content

Download Spec Sheet

download
  1. Shop all
  2. Antagonists

10-1453

HTS01037

Size

£158.00

SKU:
10-1453
Physical State:
Solid
Molecular Weight:
337.37
Purity:
98%
Purification:
HPLC Purified
Storage Conditions:
RT
Supplier:
Focus Biomolecules
CAS Number:
682741-29-3
Immunogen:
FABP (Fatty acid binding protein)
Extra Details:
Inhibits fatty acid binding proteins. Inhibits lipolysis in 3T3-L1 adipocytes and reduces LPS-stimulated inflammation in cultured macrophages. Acts as an antagonist of the protein-protein interaction between AFABP/aP2 and hormone sensitive lipase but does not activate PPARG Gamma in macrophages1. Inhibits FABP-dependent and fatty acid-stimulated leukotriene C4 biosynthesis2. Reduces intracellular free fatty acid levels, lowering macrophage inflammation and ER stress3. Reduces LPS-stimulated IL-1B Beta secretion in a mouse model4. Inhibits VLDL-induced foam cell formation5.
Shipping Conditions:
Ambient