10-1421
CZC-54252
Size
£182.00
- SKU:
- 10-1421
- Physical State:
- Solid
- Molecular Weight:
- 541.46
- Purity:
- 98%
- Storage Conditions:
- -20[o]C
- Supplier:
- Focus Biomolecules
- CAS Number:
- 1191911-27-9
- Immunogen:
- Kinase
- Extra Details:
- Novel, potent and selective inhibitor of the leucine-rich repeat kinase-2 (LRRK2), IC50 = 1.28 nM. Also inhibits G2019S mutant LRRK2, IC50 = 1.85 nM1. Attenuates the neuronal damage elicited by the action of LRRK2 G2019S mutant in primary human neurons (EC50 = 1 nM)1. The G2019S mutant is a common mutation found in familial Parkinson's disease patients2. Cell permeable.
- Shipping Conditions:
- Ambient