10-1407
PP2
Size
£158.00
- SKU:
- 10-1407
- Physical State:
- Solid
- Molecular Weight:
- 301.78
- Purity:
- 98%
- Storage Conditions:
- -20[o]C
- Supplier:
- Focus Biomolecules
- CAS Number:
- 172889-27-9
- Immunogen:
- Kinase
- Extra Details:
- Potent and selective Src family kinase inhibitor. Inhibits Lck(IC50=4 nM); Fyn (IC50=5 nM); Hck (IC50=5 nM). It displays weak inhibition of EGFR (IC50=480 nM) and no inhibition of ZAP-70 (IC50> 100 uM) and JAK2 (IC50> 50 uM)1. It is a useful probe for exploring the involvement of Src family kinases in signal transduction pathways2.
- Shipping Conditions:
- Ambient