Daminozide

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£139.00

SKU:: 10-1403
Additional Names:: N-(Dimethylamino)succinamic acid
Physical State:: Solid
Molecular Weight:: 160.17
Purity:: 98%
Storage Conditions:: RT
Supplier:: Focus Biomolecules
CAS Number:: 1596-84-5
Immunogen:: Protein demethylase
Extra Details:: A selective inhibitor of the KDM2/7 JmjC subfamily of histone demethylases. IC50=1.5, 0.55 and 2.1 uM for KDM2A, PHF8 and KDM7A respectively. Highly selective over other subfamily members (KDM3, KDM4, KDM5 and KDM6) as well as other 2-oxoglutarate oxygenases (FIH, PHD2 and BBOX1), IC50>100 uM1.