10-1393
GSK-J1
Size
£173.00
- SKU:
- 10-1393
- Physical State:
- Solid
- Molecular Weight:
- 389.46
- Purity:
- 99%
- Storage Conditions:
- RT
- Supplier:
- Focus Biomolecules
- CAS Number:
- 1373422-53-7
- Immunogen:
- Protein demethylase
- Extra Details:
- Potent and selective inhibitor of jumonji H3K27 histone demethylases JMJD3 and UTX (IC50 = 60 nM, human JMJD3). This is the first known inhibitor selective for the H3K27me3-specific JMJ subfamily which binds to the active catalytic site of the enzyme. The COOH group confers cell impermeability and as such is useful as a standard in in vitro assays. A cell permeable ethyl ester analog is also available.
- Shipping Conditions:
- Ambient