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10-1384

Epoxomicin

Size

£200.00

SKU:
10-1384
Physical State:
Solid
Molecular Weight:
554.73
Purity:
97%
Purification:
HPLC Purified
Storage Conditions:
-20[o]C
Supplier:
Focus Biomolecules
CAS Number:
134381-21-8
ABP:
No Import Docs
Immunogen:
Proteasome
Extra Details:
Epoxomicin is a potent, selective and cell permeable irreversible inhibitor of the 20S proteasome.1 It does not inhibit non-proteasomal proteases such as papain, chymotrypsin, trypsin, calpain and cathepsin B at concentrations up to 50 uM.1 Epoxomicin was isolated from Actinomycete strain Q996-17 and displayed in vivo antitumor activity against B16 melanoma cells.2 Epoxomicin caused a progressive model of Parkinson's disease in various systems.3,4,5 This model has been disputed.6,7
Shipping Conditions:
Ambient