AG-1517 HCl

Size

£168.00

SKU:: 10-1377
Additional Names:: PD153,053|SU-5271|Z-252868
Physical State:: Solid
Molecular Weight:: 360.21
Purity:: 98%
Storage Conditions:: RT
Supplier:: Focus Biomolecules
CAS Number:: 153436-54-5
Immunogen:: Kinase
Extra Details:: An ultra-potent inhibitor of epidermal growth factor receptor tyrosine kinase (EGFRK), with an IC50 of 25 pM. Inhibits other tyrosine kinases at micromolar or higher concentrations. It selectively blocks EGF-mediated cellular processes including mitogenesis, early gene expression and oncogenic transformation1. Inhibits the growth of a number of cancer cell lines2. An extremely useful tool for exploring EGF-mediated cellular signaling3.